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Showing posts with the label alzheimer's disease down syndrome

The Hidden Risks of People with Down Syndrome: Alzheimer’s Disease

 You may have heard the terms Alzheimer’s disease and Down syndrome on more than one occasion. Alzheimer’s disease , a disease that affects the brain and causes a gradual decline in memory and cognitive function, is affecting millions of families around the world. Down syndrome , a genetic condition caused by an extra copy of chromosome 21, can lead to intellectual impairment in addition to specific facial features. While the two may not seem related at first glance, research shows that people with Down syndrome are actually at a higher risk of developing Alzheimer’s disease as they age . This finding has important implications for our understanding of the connection between the two conditions and how to more effectively manage and provide care. Key Points People with Down syndrome have an excess of the APP gene on chromosome 21, which increases beta-amyloid protein, which increases their risk of Alzheimer’s disease. More than half of people with Down syndrome will experience cogn...