Alzheimer’s disease is one of the most common neurodegenerative disorders, primarily characterized by memory loss, cognitive decline, and behavioral changes. A key pathological feature of this disease is the formation of amyloid plaques in the brain. The accumulation of these plaques significantly contributes to the damage of nerve cells and the deterioration of brain function. This article will explore the formation of Alzheimer’s plaques, their impact on the brain, and current research focused on targeting these plaques as a potential treatment for the disease. Key Points Amyloid plaques : A primary hallmark of Alzheimer’s disease, formed by the abnormal accumulation of beta-amyloid proteins in the brain. Memory and cognitive impairment : Plaques disrupt communication between neurons, leading to memory loss and cognitive decline. Plaque formation mechanism : Abnormal folding and clearance failure of beta-amyloid proteins are key to plaque formation. Prevention and treatment : Re...
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